Skin Biology - Skincare Products Based on Integrity and True Science™

Healthful Actions acts by:

Effect on Skin:

Anti-inflammatory and anti-oxidant

• Booses the skin's anti-oxidant defenses by increasing copper into superoxide dismutase

• Decreases production of TGF-beta, the scar forming protein

• Blocks dermal damage by interleukin-1 and TNF-alpha

• Calmer skin

• Less irritation

• Reduced scarring

• Removes damaged skin and proteins

• Activate metalloproteinases

• Clear radiant complexion free of blemishes and bumps

• Rebuilds skin

• Supports the synthesis of new collagen and elastin

• Helps fibroblasts contract collagen strands for a tighter epidermis

• Increases keratinocyte production

• Helps increase water-holding proteoglycans

• Firmer skin with increased elasticity

• Reduced wrinkles

• Smoother complexion

• Enhanced moisturization

• Revs up the blood's microcirculation

• Vital nutrients provide a youthful glow

• Repairs, thickens, and tightens skin barrier

• Less skin evaporation keeps skin dewy and moist

• Healthy barrier that resists viruses and bacteria

• Enlarges size of small (nearly invisible) vellus hair follicles that produce stem cells for skin

• Increased stem cells nourish the skin

Have you ever wondered why babies have such beautiful skin? When we are children, our skin naturally remodels and renews itself unveiling a youthful glow. Remodeling plays the most crucial role of skincare, the Sine Non Qua (that which cannot be done without). Remodeling is the cycle of renewal that removes older skin, scars, blemishes, and damaged proteins while replacing them with a new, younger complexion. However, as we age, this process slows down and produces a dry, wrinkled, inelastic skin populated by unsightly lesions. Remodeling offers a mechanism of repair that removes damaged materials from the skin and creates new, tight, blemish-free skin.

Beyond Retinoic Acid - The Natural Human Signals for Skin Remodeling

Retinoic acid (retin-A), the first widely used product to remodel skin, reduces fine lines – but at a price. This highly acidic product unleashes some unpleasant side effects such as chronic irritation and redness. When Dr. Loren Pickart discovered Skin Remodeling Copper Peptides (SRCPs), he found that these natural molecules signal the skin to reduce wrinkles without irritation. They increase the skin's internal water-holding proteins which moisturize skin. Clinical studies have found SRCPs more effective in restoring the skin's collagen than Vitamin C or retin-A. Collagen and elastin are rebuilt, giving you a firmer, more elastic skin. The advantage of these peptides over retin-A is that they are non-irritating and possess strong anti-inflammatory properties. In every comparative clinical study, skin remodeling copper peptides have proved superior to Retin-A(R), Vitamin C creams, and Kinerase(R) in terms of reducing wrinkles, blotchiness and improving firmness. SRCPs also help activate your skin's system to remove damaged collagen, elastin and reduce the skin's production of the scar-producing factor, TGF-beta.

Skin Biology's Improved Remodeling Products

Skin Biology's new and patented Second Generation Copper-Peptides are breakdown-resistant, long acting, and produce strong skin regeneration and remodeling. They work synergistically with hydroxy acids and Retin-A for enhanced rejuvenation. In contrast, the single peptides (tripeptides or pentapeptides) in many cosmetics tend to be fragile, short-acting, and cannot be used with hydroxy acids. Extensive safety testing has proven Skin Biology's Copper-Peptides to be non-allergenic and non-irritating. They have neither the allergenic sensitization problems of the bacterial produced Copper-Peptides nor the biological inactivity of copper complexes ("colorless-copper") used by some cosmetic companies. Microbiological studies of Skin Biology products have found them to inhibit the growth of dangerous, pathogenic skin bacteria.

What To Expect

Watch copper peptides turn back the clock on skin aging!

In a week - Skin color and "glow" improves as the blood capillary network is rebuilt. Lifeless and graying skin regains the rosy glow of youth.

In a month – Skin becomes better moisturized as the skin barrier tightens and the water-holding proteins (proteoglycans) increase. Many of our customers tell us they no longer need moisturizers. Skin firms and tightens as new collagen and elastin replaces old damaged proteins. The skin slowly thickens and appears much younger and more resilient.

Over several months - Skin lesions and scars slowly vanish while wrinkles are reduced. The result is a younger-looking, smoother, blemish-free skin. This process can be hastened by applying hydroxy acids to speed exfoliation. Clear, blemish-free skin is the number one factor in interpersonal attraction based on psychological studies of 170 human cultures.

These new improved, breakdown resistant Copper-Peptides are available exclusively in Skin Biology products. Five US patents have been granted to Skin Biology for the exclusive use of this technology (US 5,698,184, US 5,382,431, 5,858,993, US 5,888,522, US 5,554,375, and pending patents).

Although you may find other companies selling Copper-Peptide products, our tests reveal they provide little or at best marginal activity. In fact, there are peptide cosmetics that actually inhibit skin repair. Some contain peptides derived from yeast or bacteria that can cause skin allergies and asthma. Many companies marketing harmful forms of copper peptides have been fined repeatedly by the US Federal Trade Commission for false advertising. "Clinically proven" is a meaningless advertising slogan that can imply virtually anything. For more information on various Copper-Peptides, please visit: Comparing Copper-Peptides

Distinguishing Between Remodeling Copper-Peptides, Aminopeptides, and Pentapeptides

Many peptide products claim to improve skin by increasing the production of collagen, elastin, and proteoglycans. Manufacturers state these peptides act much like Transforming Factor Beta-1 (TGF-beta 1). TGF-beta 1 and peptides with similar actions were intensively tested in wound healing studies about ten years ago. Such peptides failed because, while they rapidly healed wounds, they also produced heavy and unacceptable scarring. If you use these new peptides, be cautious. We have received several reports indicating hard spots on the skin or lumps under the skin after a month of using these products. With TGF beta, there were further concerns over potential side effects. TGF-beta-1 can make normal cells grow like cancer cells and may speed the growth of breast cancer. It also may play a role in the development of kidney failure. See Comparing Copper-Peptides.

Remodeling Copper Peptides vs
Aminopeptides and Pentapeptides

Skin Remodeling Copper Peptides

Aminopeptides and Pentapeptides

Increase collagen, elastin, proteoglycans - Yes

Yes

Activate removal of damaged proteins and older skin - Yes

Effect on TGF-beta (scar forming and skin hardening hormone): Suppresses formation of TGF beta

Said to similar in action to TGF beta

Effect on Interleukin-1 (skin damaging cytokine): Blocks Interleukin-1 damage on cells

No effect

Powerful antioxidant actions against oxygen radicals

No antioxidant actions

Naturally present in the human body - Yes; present in human blood at 200 micrograms per liter

No, not normally present

Cell Protectant: Aids the growth and survival of many types of mammalian cells in culture